Epetraborole

DB11744InvestigationalSmall molecule

Epetraborole has been used in trials studying the treatment of Infections, Bacterial, Infections, Intestinal, Infections, Urinary Tract, and Community-acquired Infection.

Mechanism: Pharmacologically active on Leucine--tRNA ligase, mitochondrial
Curator reviewed
Formula / weight: C₁₁H₁₆BNO₄ · 237.06 g/mol (avg)
Code names: AN-3365 · GSK-2251052

Resolves to

Compound

UNII6MC93Z2DF9CAS1093643-37-8ChEMBLCHEMBL3549142PubChem46836890

Structure

InChIKeyFXQIIDINBDJDKL-SNVBAGLBSA-NSMILESNC[C@H]1OB(O)C2=C1C=CC=C2OCCCO

Targets

Q15031LARS2

What you can answer from here — as of September 25, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

56Drug interactionsStructured to mechanism, not free text

11Clinical trialsPhase, status and sponsor resolved per trial

12+ReferencesStructured and connected to the statements they support

Which drugs share a target with Epetraborole, and which of those have an active Phase 3 trial?

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