Basimglurant

DB11833InvestigationalSmall molecule

Basimglurant has been used in trials studying the diagnostic and treatment of Depression, Fragile X Syndrome, and Major Depressive Disorder.

Mechanism: Pharmacologically active on Metabotropic glutamate receptor 5
Curator reviewed
Formula / weight: C₁₈H₁₃ClFN₃ · 325.77 g/mol (avg)
Code names: NOE-101 · RG-7090 · RO-4917523

Resolves to

Compound

Structure

InChIKeyUPZWINBEAHDTLA-UHFFFAOYSA-NSMILESCC1=NC(C#CC2=CC=NC(Cl)=C2)=C(C)N1C1=CC=C(F)C=C1

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

8Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Basimglurant, and which of those have an active Phase 3 trial?

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