Alvelestat

DB11863InvestigationalSmall molecule

Alvelestat has been investigated for the basic science of Chronic Obstructive Pulmonary Disease.

Chemical structure of Alvelestat
Mechanism
Curator reviewed
Formula / weight
C25H22F3N5O4S · 545.54 g/mol (avg)
Code names
AZD-9668 · MPH966

Resolves to

Compound
UNII6Y5629322XCAS848141-11-7ChEMBLCHEMBL3617964PubChem71587812
Structure
InChIKeyQNQZWEGMKJBHEM-UHFFFAOYSA-NSMILESCN1N=CC=C1C1=C(C)N(C2=CC=CC(=C2)C(F)(F)F)C(=O)C(=C1)C(=O)NCC1=NC=C(C=C1)S(C)(=O)=O
Targets
P08246ELANE

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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13Clinical trialsPhase, status and sponsor resolved per trial
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5+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Alvelestat, and which of those have an active Phase 3 trial?

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