3,3'-diindolylmethane

DB11875InvestigationalSmall molecule

Diindolylmethane has been used in trials studying the prevention and treatment of SLE, Prostate Cancer, Cervical Dysplasia, Stage I Prostate Cancer, and Stage II Prostate Cancer, among others.

Chemical structure of 3,3'-diindolylmethane
Mechanism
Curator reviewed
Formula / weight
C17H14N2 · 246.313 g/mol (avg)
Also known as
Diindolylmethane

Resolves to

Compound
UNIISSZ9HQT61ZCAS1968-05-4ChEMBLCHEMBL446452ChEBI50182PubChem3071
Clinical / RWD
RxNorm1603521
Structure
InChIKeyVFTRKSBEFQDZKX-UHFFFAOYSA-NSMILESC(C1=CNC2=CC=CC=C12)C1=CNC2=CC=CC=C12
Targets
P35869AHRP22736NR4A1Q9NQS5GPR84

What you can answer from here — as of July 07, 2026

3Protein targetsEach mapped to UniProt, with action and pharmacological action
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8Clinical trialsPhase, status and sponsor resolved per trial
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1Marketed productAcross 1 country and 1 labeller
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6+ReferencesStructured and connected to the statements they support
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Which drugs share a target with 3,3'-diindolylmethane, and which of those have an active Phase 3 trial?

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