Sultamicillin

DB12127ApprovedWithdrawnSmall molecule

Sultamicillin is a mutual prodrug of ampicillin and sulbactam useful in the treatment of infections caused by beta-lactamase-producing bacteria. Sultamicillin has been used in trials studying the prevention and treatment of Ventilator Associated Pneumonia and Chronic Obstructive Pulmonary Disease (COPD).

Mechanism: Pharmacologically active on Beta-lactamase
Curator reviewed
Formula / weight: C₂₅H₃₀N₄O₉S₂ · 594.65 g/mol (avg)
Code names: CP-49,952 · VD-1827

Resolves to

Compound

UNII65DT0ML581CAS76497-13-7ChEMBLCHEMBL506110ChEBI51770PubChem444022

Clinical / RWD

ATCJ01CR04ATCJ01CR50

Structure

InChIKeyOPYGFNJSCUDTBT-PMLPCWDUSA-NSMILES[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CC=CC=C1)C(=O)OCOC(=O)[C@@H]1N2C(=O)C[C@@]2([H])S(=O)(=O)C1(C)C

Targets

P00807blaZ

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

194Drug interactionsStructured to mechanism, not free text

2Clinical trialsPhase, status and sponsor resolved per trial

1Structured indicationCondition, population, route and combination as fields, not prose

1ContraindicationEach with its own population and attribute set

140Marketed productsAcross 8 countries and 30 labellers

2ATC codesIncluding every combination product, plus 12 drug categories

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Sultamicillin, and which of those have an active Phase 3 trial?

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