PF-03715455

DB12138InvestigationalSmall molecule

PF-03715455 has been used in trials studying the treatment of Asthma, Pulmonary Disease, Chronic Obstructive, and Chronic Obstructive Pulmonary Disease (COPD).

Mechanism: Pharmacologically active on Mitogen-activated protein kinase 14
Curator reviewed
Formula / weight: C₃₅H₃₄ClN₇O₃S₂ · 700.273 g/mol (avg)
Code names: PF-03715455

Resolves to

Compound

UNII0TJ631J0KPCAS1056164-52-3ChEMBLCHEMBL1938400PubChem11714580

Structure

InChIKeyVGEXRDWWPSGZDH-UHFFFAOYSA-NSMILESCC(C)(C)C1=NN(C(NC(=O)NCC2=CC=CC=C2SC2=CN3C(C=C2)=NN=C3C2=CC=CC=C2SCCO)=C1)C1=CC=C(O)C(Cl)=C1

Targets

Q16539MAPK14

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with PF-03715455, and which of those have an active Phase 3 trial?

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