Exatecan

DB12185InvestigationalSmall molecule

Exatecan has been used in trials studying the treatment of Sarcoma, Leukemia, Lymphoma, Lung Cancer, and Liver Cancer, among others.

Chemical structure of Exatecan
Mechanism
Curator reviewed
Formula / weight
C24H22FN3O4 · 435.455 g/mol (avg)
Code names
DX-8951 · DX-8951f

Resolves to

Compound
UNIIOC71PP0F89CAS171335-80-1ChEMBLCHEMBL1614650ChEBI135709PubChem151115
Structure
InChIKeyZVYVPGLRVWUPMP-FYSMJZIKSA-NSMILESCC[C@@]1(O)C(=O)OCC2=C1C=C1N(CC3=C1N=C1C=C(F)C(C)=C4CC[C@H](N)C3=C14)C2=O
Targets
P11387TOP1

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
39Drug interactionsStructured to mechanism, not free text
Sign in
27Clinical trialsPhase, status and sponsor resolved per trial
Sign in
5+ReferencesStructured and connected to the statements they support
Sign in

Which drugs share a target with Exatecan, and which of those have an active Phase 3 trial?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In