GDC-0917

DB12336InvestigationalSmall molecule

CUDC-427 has been used in trials studying the treatment of LYMPHOMA and Solid Cancers.

Mechanism: Pharmacologically active on Baculoviral IAP repeat-containing protein 2
Curator reviewed
Formula / weight: C₂₉H₃₆N₆O₄S · 564.71 g/mol (avg)
Code names: CUDC-427

Resolves to

Compound

Structure

InChIKeyHSHPBORBOJIXSQ-HARLFGEKSA-NSMILESCN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)NC1=C(N=C(S1)C1=NC=CO1)C1=CC=CC=C1

Targets

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with GDC-0917, and which of those have an active Phase 3 trial?

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