Zamicastat

DB12389InvestigationalSmall molecule

Zamicastat has been used in trials studying the treatment of Hypertension and Chronic Heart Failure.

Chemical structure of Zamicastat
Mechanism
Curator reviewed
Formula / weight
C21H21F2N3OS · 401.48 g/mol (avg)

Resolves to

Compound
UNIIYLU32D0DNVCAS1080028-80-3PubChem25052630
Structure
InChIKeyZSSLCFLHEFXANG-GOSISDBHSA-NSMILESFC1=CC(F)=C2OC[C@@H](CC2=C1)N1C(=S)NC=C1CCNCC1=CC=CC=C1
Targets
P09172DBH

What you can answer from here — as of August 30, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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6Clinical trialsPhase, status and sponsor resolved per trial
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3+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Zamicastat, and which of those have an active Phase 3 trial?

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