DSM-265

DB12397InvestigationalSmall molecule

DSM265 has been used in trials studying the prevention and treatment of Malaria.

Mechanism: Pharmacologically active on Dihydroorotate dehydrogenase (quinone), mitochondrial
Curator reviewed
Formula / weight: C₁₄H₁₂F₇N₅S · 415.33 g/mol (avg)
Also known as: 2-(1,1-Difluoroethyl)-5-methyl-N-[4-(pentafluoro-λ6-sulfanyl)phenyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine
Code names: DSM 265

Resolves to

Compound

Structure

InChIKeyOIZSVTOIBNSVOS-UHFFFAOYSA-NSMILESCC1=NC2=NC(=NN2C(NC2=CC=C(C=C2)S(F)(F)(F)(F)F)=C1)C(C)(F)F

Targets

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

7Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with DSM-265, and which of those have an active Phase 3 trial?

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