HSD-016

DB12419InvestigationalSmall molecule

Hsd 016 is under investigation in clinical trial NCT00838461 (Study Evaluating the Safety, Pharmacokinetics (PK), and Pharmacodynamices (PD) of HSD-016).

Mechanism: Pharmacologically active on 11-beta-hydroxysteroid dehydrogenase 1
Curator reviewed
Formula / weight: C₂₁H₂₁F₇N₂O₃S · 514.46 g/mol (avg)
Code names: HSD-016

Resolves to

Compound

UNIIC4I13768E1CAS946396-92-5PubChem16721125

Structure

InChIKeyZWASRJHIEFYJGL-BFUOFWGJSA-NSMILESC[C@@H]1CN(CCN1S(=O)(=O)C1=CC=CC(=C1)[C@@](C)(O)C(F)(F)F)C1=CC=C(F)C=C1C(F)(F)F

Targets

P28845HSD11B1

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with HSD-016, and which of those have an active Phase 3 trial?

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