SCH-486757

DB12782InvestigationalSmall molecule

Sch 486757 has been used in trials studying the treatment of Cough.

Chemical structure of SCH-486757
Mechanism
Curator reviewed
Formula / weight
C24H23Cl2N3O · 440.37 g/mol (avg)
Code names
SCH 486757

Resolves to

Compound
UNII2HV668N62TCAS524019-25-8PubChem11597355
Structure
InChIKeyMQWMHMZNBGQNMT-XHNJZIHCSA-NSMILESO[C@]1(C[C@@H]2CC[C@H](C1)N2C(C1=CC=CC=C1Cl)C1=CC=CC=C1Cl)C1=NC=CC=N1
Targets
P41146OPRL1

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
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1Clinical trialPhase, status and sponsor resolved per trial
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2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with SCH-486757, and which of those have an active Phase 3 trial?

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