Clazakizumab

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Clazakizumab
Accession Number
DB12849
Description

Clazakizumab has been used in trials studying the treatment of Rheumatoid Arthritis.

Type
Biotech
Groups
Investigational
Biologic Classification
Protein Based Therapies
Monoclonal antibody (mAb)
Protein Chemical Formula
Not Available
Protein Average Weight
Not Available
Sequences
Not Available
Synonyms
  • BMS-945429

Pharmacology

Indication
Not Available
Contraindications & Blackbox Warnings
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbciximabThe risk or severity of adverse effects can be increased when Abciximab is combined with Clazakizumab.
AdalimumabThe risk or severity of adverse effects can be increased when Adalimumab is combined with Clazakizumab.
AlemtuzumabThe risk or severity of adverse effects can be increased when Alemtuzumab is combined with Clazakizumab.
AlirocumabThe risk or severity of adverse effects can be increased when Alirocumab is combined with Clazakizumab.
AnsuvimabThe risk or severity of adverse effects can be increased when Clazakizumab is combined with Ansuvimab.
Anthrax immune globulin humanThe risk or severity of adverse effects can be increased when Anthrax immune globulin human is combined with Clazakizumab.
Antilymphocyte immunoglobulin (horse)The risk or severity of adverse effects can be increased when Antilymphocyte immunoglobulin (horse) is combined with Clazakizumab.
Antithymocyte immunoglobulin (rabbit)The risk or severity of adverse effects can be increased when Antithymocyte immunoglobulin (rabbit) is combined with Clazakizumab.
Asfotase alfaThe risk or severity of adverse effects can be increased when Asfotase alfa is combined with Clazakizumab.
AtezolizumabThe risk or severity of adverse effects can be increased when Atezolizumab is combined with Clazakizumab.
Additional Data Available
  • Extended Description
    Extended Description
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    Extended description of the mechanism of action and particular properties of each drug interaction.

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  • Severity
    Severity
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    A severity rating for each drug interaction, from minor to major.

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  • Evidence Level
    Evidence Level
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    A rating for the strength of the evidence supporting each drug interaction.

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  • Action
    Action
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Food Interactions
Not Available

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
Not Available
Kingdom
Organic Compounds
Super Class
Organic Acids
Class
Carboxylic Acids and Derivatives
Sub Class
Amino Acids, Peptides, and Analogues
Direct Parent
Peptides
Alternative Parents
Not Available
Substituents
Not Available
Molecular Framework
Not Available
External Descriptors
Not Available

Chemical Identifiers

UNII
4S38Z8RA9O
CAS number
1236278-28-6

References

General References
Not Available
PubChem Substance
347911396
Wikipedia
Clazakizumab

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3RecruitingTreatmentAntibody-mediated Rejection1
2Active Not RecruitingTreatmentCoronavirus Disease 2019 (COVID‑19)2
2CompletedTreatmentAntibody-mediated Rejection1
2CompletedTreatmentPsoriatic Arthritis1
2CompletedTreatmentRheumatoid Arthritis2
2Enrolling by InvitationTreatmentCoronavirus Disease 2019 (COVID‑19) / Respiratory Failure1
2Not Yet RecruitingTreatmentCoronavirus Disease 2019 (COVID‑19)1
2RecruitingTreatmentAsthma1
2RecruitingTreatmentCoronavirus Disease 2019 (COVID‑19)1
2RecruitingTreatmentCoronavirus Disease 2019 (COVID‑19) / Covid-19 Infection1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on October 20, 2016 18:42 / Updated on June 12, 2020 10:53

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