Interleukin-6

BE0000918ProteinHumansIL6

Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. It is acted on by 21 drugs in DrugBank.

Gene name
IL6
UniProtKB entry
P05231Swiss-Prot
Cellular location
Secreted
Residues / weight
212 residues · 23,718 Da
Also known as
B-cell stimulatory factor 2 · BSF-2 · CDF · CTL differentiation factor · Hybridoma growth factor

Resolves to

Protein
UniProtP05231UniProt nameIL6_HUMAN
Gene
HGNCHGNC:6018NCBI Gene3569GenBank32674GeneCardsIL6
Pharmacology
KEGGhsa:3569
Structure
PDB1ALUPDB1IL6PDB1P9M
Drugs

What you can answer from here — as of September 07, 2019

21DrugsApproved to experimental, with action, bond type and pharmacological action
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162Clinical trialsTrials of drugs acting on it, by phase and status
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47GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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51+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Interleukin-6, how selective are they, and which programs against it are still in active trials?

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