MK-8245

DB13024InvestigationalSmall molecule

MK-8245 has been used in trials studying the treatment of Type 2 Diabetes Mellitus.

Mechanism: Pharmacologically active on Stearoyl-CoA desaturase
Curator reviewed
Formula / weight: C₁₇H₁₆BrFN₆O₄ · 467.255 g/mol (avg)
Code names: MK-8245

Resolves to

Compound

Structure

InChIKeyUJEAABFSXKCSGI-UHFFFAOYSA-NSMILESOC(=O)CN1N=NC(=N1)C1=CC(=NO1)N1CCC(CC1)OC1=C(Br)C=CC(F)=C1

Targets

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with MK-8245, and which of those have an active Phase 3 trial?

Create a free account or log in to explore the full data card.