Pruvanserin

DB13094InvestigationalSmall molecule

Pruvanserin has been used in trials studying the treatment of Sleep Initiation and Maintenance Disorders.

Mechanism: Pharmacologically active on 5-hydroxytryptamine receptor 2A
Curator reviewed
Formula / weight: C₂₂H₂₁FN₄O · 376.435 g/mol (avg)
Code names: EMD-390920 · LSN-2422347 · LY-2422347

Resolves to

Compound

Structure

InChIKeyAQRLDDAFYYAIJP-UHFFFAOYSA-NSMILESFC1=CC=C(CCN2CCN(CC2)C(=O)C2=C3NC=C(C#N)C3=CC=C2)C=C1

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with Pruvanserin, and which of those have an active Phase 3 trial?

Create a free account or log in to explore the full data card.