5-hydroxytryptamine receptor 2A

BE0000451ProteinHumansHTR2A

G protein-coupled receptor for 5-hydroxytryptamine (serotonin) (PubMed:1330647, PubMed:18703043, PubMed:19057895, PubMed:21645528, PubMed:22300836, PubMed:35084960, PubMed:38552625). It is acted on by 156 drugs in DrugBank.

Gene name
HTR2A
UniProtKB entry
P28223Swiss-Prot
Cellular location
Cell membrane
Residues / weight
471 residues · 52,603 Da
Also known as
5-HT-2 · 5-HT-2A · HTR2 · Serotonin receptor 2A

Resolves to

Protein
UniProtP28223UniProt name5HT2A_HUMAN
Gene
HGNCHGNC:5293NCBI Gene3356GenBank36431GeneCardsHTR2A
Pharmacology
IUPHAR/GtoPdb6KEGGhsa:3356
Structure
PDB6A93PDB6A94PDB6WGT
Drugs

What you can answer from here — as of September 07, 2019

156DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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30GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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549+ReferencesStructured and connected to the statements they support
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Which approved drugs act on 5-hydroxytryptamine receptor 2A, how selective are they, and which programs against it are still in active trials?

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