AZD-8418

DB13102InvestigationalSmall molecule

Azd8418 is under investigation in clinical trial NCT01027234 (This Study Will Assess the Safety and Tolerability of AZD8418 After Single Increasing Oral Doses).

Mechanism: Pharmacologically active on Metabotropic glutamate receptor 2
Curator reviewed
Formula / weight: C₁₉H₂₀ClN₃O₃ · 373.84 g/mol (avg)
Code names: AZD8418

Resolves to

Compound

UNII7U6B825568CAS1198309-73-7PubChem44556193

Structure

InChIKeyMCPBSUCAISQZQK-JTQLQIEISA-NSMILESC[C@@H](C1CC1)N1CC2=CC(=CC(Cl)=C2C1=O)C1=CC(=NO1)C(=O)N(C)C

Targets

Q14416GRM2

What you can answer from here — as of July 07, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

1+ReferenceStructured and connected to the statements they support

Which drugs share a target with AZD-8418, and which of those have an active Phase 3 trial?

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