Varegacestat

DB13126InvestigationalSmall molecule

BMS-986115 has been used in trials studying the treatment of Various Advanced Cancer.

Chemical structure of Varegacestat
Formula / weight
C26H25F7N4O3 · 574.5 g/mol (avg)
Code names
AL102 · BMS-986115

Resolves to

Compound
UNIILSK1L593UUCAS1584647-27-7ChEMBLCHEMBL3911164PubChem73388393
Structure
InChIKeySRJNRAQUSAVENA-GSHUGGBRSA-NSMILESCC1=CC=CC2=C1NC(=O)[C@@H](NC(=O)[C@H](CCC(F)(F)F)[C@H](CCC(F)(F)F)C(N)=O)N=C2C1=CC=CC(F)=C1

What you can answer from here — as of September 21, 2026

5Clinical trialsPhase, status and sponsor resolved per trial
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Which companies are running trials of Varegacestat, in which indications and phases, and which of those programs are still active?

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