Tiazofurine

DB13243ExperimentalSmall molecule

Tiazofurine has potential clinical use in cancer treatment as it is a potential inhibitor of Inosine- 5’-monophosphate (IMP) dehydrogenase .

Chemical structure of Tiazofurine
Formula / weight
C9H12N2O5S · 260.267 g/mol (avg)
Also known as
2-(β-D-ribofuranosyl)-4-thiazolecarboxamide · 2-Beta-D-ribofuranosyl-4-thiazolecarboxamide · 2-β-D-ribofuranosyl-4-thiazolecarboxamide · TCAR · Tiazofurin
Code names
CI-909 · NSC-286193

Resolves to

Compound
UNIIULJ82834RECAS60084-10-8ChEMBLCHEMBL108358ChEBI90239KEGGD06130
Clinical / RWD
ATCL01XX18
Structure
InChIKeyFVRDYQYEVDDKCR-DBRKOABJSA-NSMILESNC(=O)C1=CSC(=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
Targets
P20839IMPDH1

What you can answer from here — as of January 29, 2025

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
39Drug interactionsStructured to mechanism, not free text
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1ATC codeIncluding every combination product, plus 8 drug categories
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2+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Tiazofurine, and which of those have an active Phase 3 trial?

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