Hydrochloric acid

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Summary

Hydrochloric acid is a strong acid used to adjust the pH of injections and ophthalmic solutions.

Generic Name
Hydrochloric acid
DrugBank Accession Number
DB13366
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 36.461
Monoisotopic: 35.976677739
Chemical Formula
ClH
Synonyms
  • Chlorowodor
  • Chlorure d'hydrogène
  • Chlorwasserstoff
  • Cloruro de hidrógeno
  • Hydrochloric acid
  • Hydrogenchlorid
  • Wasserstoffchlorid
External IDs
  • E-507
  • INS NO.507
  • INS-507
  • NSC-77365

Pharmacology

Indication

Not Available

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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Products

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Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Aminomix 1 Novum - InfusionslösungHydrochloric acid (1.47 ml/L) + Acetic acid (4.5 g/L) + Alanine (7 g/L) + Arginine (6 g/L) + Calcium chloride (0.294 g/L) + D-glucose monohydrate (220 g/L) + Glycine (5.5 g/L) + Histidine (1.5 g/L) + Isoleucine (2.5 g/L) + Leucine (3.7 g/L) + Lysine hydrochloride (4.125 g/L) + Magnesium chloride hexahydrate (0.61 g/L) + Methionine (2.15 g/L) + Phenylalanine (2.55 g/L) + Potassium hydroxide (1.981 g/L) + Proline (5.6 g/L) + Serine (3.25 g/L) + Sodium chloride (1.169 g/L) + Sodium glycerophosphate (4.59 g/L) + Taurine (0.5 g/L) + Threonine (2.2 g/L) + Tryptophan (1 g/L) + Tyrosine (0.2 g/L) + Valine (3.1 g/L) + Zinc chloride (0.00545 g/L)SolutionIntravenousFresenius Kabi Austria Gmb H2005-12-05Not applicableAustria flag
Aminomix 2 Novum - InfusionslösungHydrochloric acid (1.47 ml/L) + Acetic acid (4.5 g/L) + Alanine (7 g/L) + Arginine (6 g/L) + Calcium chloride (0.294 g/L) + Dextrose, unspecified form (120 g/L) + Glycine (5.5 g/L) + Histidine (1.5 g/L) + Isoleucine (2.5 g/L) + Leucine (3.7 g/L) + Lysine hydrochloride (4.125 g/L) + Magnesium chloride hexahydrate (0.61 g/L) + Methionine (2.15 g/L) + Phenylalanine (2.55 g/L) + Potassium hydroxide (1.981 g/L) + Proline (5.6 g/L) + Serine (3.25 g/L) + Sodium chloride (1.169 g/L) + Sodium glycerophosphate (4.59 g/L) + Taurine (0.5 g/L) + Threonine (2.2 g/L) + Tryptophan (1 g/L) + Tyrosine (0.2 g/L) + Valine (3.1 g/L) + Zinc chloride (0.00545 g/L)SolutionIntravenousFresenius Kabi Austria Gmb H2005-12-05Not applicableAustria flag
SYVICROM ® 4% SOLUCION OFTALMICAHydrochloric acid (0 mL) + Benzalkonium chloride (0.1 mg) + Cromoglicate sodium (40 mg) + Edetate disodium anhydrous (1 mg) + Sodium hydroxide (0 mL) + Water (1 mL)SolutionOphthalmicOPHARM LTDA.2019-05-21Not applicableColombia flag

Categories

ATC Codes
B05XA13 — Hydrochloric acidA09AB03 — Hydrochloric acid
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as halogen hydrides. These are inorganic compounds in which the heaviest atom bonded to a hydrogen atom is a halogen.
Kingdom
Inorganic compounds
Super Class
Homogeneous non-metal compounds
Class
Halogen organides
Sub Class
Halogen hydrides
Direct Parent
Halogen hydrides
Alternative Parents
Inorganic hydrides
Substituents
Halogen hydride / Inorganic hydride
Molecular Framework
Not Available
External Descriptors
hydrogen halide, mononuclear parent hydride, chlorine molecular entity (CHEBI:17883) / a small molecule (HCL)
Affected organisms
Not Available

Chemical Identifiers

UNII
QTT17582CB
CAS number
7647-01-0
InChI Key
VEXZGXHMUGYJMC-UHFFFAOYSA-N
InChI
InChI=1S/ClH/h1H
IUPAC Name
hydrogen chloride
SMILES
Cl

References

General References
Not Available
Human Metabolome Database
HMDB0002306
KEGG Drug
D02057
KEGG Compound
C01327
ChemSpider
307
RxNav
5486
ChEBI
17883
ChEMBL
CHEMBL1231821
Wikipedia
Hydrochloric_acid

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedTreatmentThyroid Eye Disease1
2RecruitingTreatmentEfficacy of Ensatinib in This Subset of Patients / Second Generation ALK-TKI is Resistant / The Diagnosis Was ALK Positive NSCLC1
Not AvailableRecruitingTreatmentCentral Line Associated Blood Stream Infections (CLABSI)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, solutionIntravenous
SolutionIntravenous
SolutionOphthalmic
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.0 mg/mLALOGPS
logP-1.3ALOGPS
logP0.61Chemaxon
logS1.08ALOGPS
pKa (Strongest Acidic)-7Chemaxon
Physiological Charge-1Chemaxon
Hydrogen Acceptor Count0Chemaxon
Hydrogen Donor Count0Chemaxon
Polar Surface Area0 Å2Chemaxon
Rotatable Bond Count0Chemaxon
Refractivity6.42 m3·mol-1Chemaxon
Polarizability2.65 Å3Chemaxon
Number of Rings0Chemaxon
Bioavailability1Chemaxon
Rule of FiveYesChemaxon
Ghose FilterNoChemaxon
Veber's RuleYesChemaxon
MDDR-like RuleNoChemaxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted GC-MS Spectrum - GC-MSPredicted GC-MSNot Available
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available
MS/MS Spectrum - Linear Ion Trap , negativeLC-MS/MSsplash10-0a4i-0000009000-8651ed5a563be0ad942f
MS/MS Spectrum - Linear Ion Trap , negativeLC-MS/MSsplash10-0a4i-0000009000-6193af2f15253417208c
MS/MS Spectrum - Linear Ion Trap , positiveLC-MS/MSsplash10-014i-0000900000-5818c00db6f91eb3e74d

Drug created at June 23, 2017 20:40 / Updated at June 02, 2021 20:04