Transient receptor potential cation channel subfamily V member 1

BE0001023ProteinHumansTRPV1

Non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli (PubMed:11050376, PubMed:11243859, PubMed:11226139, PubMed:12077606). It is acted on by 47 drugs in DrugBank.

Gene name
TRPV1
UniProtKB entry
Q8NER1Swiss-Prot
Cellular location
Postsynaptic cell membrane
Residues / weight
839 residues · 94,955 Da
Also known as
Capsaicin receptor · Osm-9-like TRP channel 1 · OTRPC1 · TrpV1 · Vanilloid receptor 1

Resolves to

Protein
UniProtQ8NER1UniProt nameTRPV1_HUMAN
Gene
HGNCHGNC:12716NCBI Gene7442GenBank8977866GeneCardsTRPV1
Pharmacology
IUPHAR/GtoPdb507KEGGhsa:7442
Structure
PDB6L93PDB8GF8PDB8GF9
Drugs

What you can answer from here — as of September 07, 2019

47DrugsApproved to experimental, with action, bond type and pharmacological action
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2Clinical trialsTrials of drugs acting on it, by phase and status
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13GO termsFunction, process and component, as structured annotations
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3Pfam domainsDomain architecture mapped to Pfam families and clans
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123+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Transient receptor potential cation channel subfamily V member 1, how selective are they, and which programs against it are still in active trials?

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