This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Explore a selection of our essential drug information below, or:
Identification
- Summary
Fenticonazole is an imidazole antifungal used to treat a variety of topical fungal infections.
- Generic Name
- Fenticonazole
- DrugBank Accession Number
- DB13434
- Background
Not Available
- Type
- Small Molecule
- Groups
- Experimental
- Structure
Structure for Fenticonazole (DB13434)
- Weight
- Average: 455.4
Monoisotopic: 454.0673398 - Chemical Formula
- C24H20Cl2N2OS
- Synonyms
- Fenticonazole
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Associated Conditions
Indication Type Indication Combined Product Details Approval Level Age Group Patient Characteristics Dose Form Treatment of Balanitis ••• ••• •••••• Treatment of Balanoposthitis ••• ••• •••••• Treatment of Candidiasis of skin nos ••• ••• •••••• Treatment of Dermatomycoses ••• ••• •••••• Treatment of Erythrasma ••• ••• •••••• - Contraindications & Blackbox Warnings
Prevent Adverse Drug Events TodayTap into our Clinical API for life-saving information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events with our Clinical API- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates. View sample adverse effects data in our new Data Library!Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Product Ingredients
Ingredient UNII CAS InChI Key Fenticonazole nitrate 8V4JGC8YRF 73151-29-8 FJNRUWDGCVDXLU-UHFFFAOYSA-N
Categories
- ATC Codes
- D01AC12 — Fenticonazole
- D01AC — Imidazole and triazole derivatives
- D01A — ANTIFUNGALS FOR TOPICAL USE
- D01 — ANTIFUNGALS FOR DERMATOLOGICAL USE
- D — DERMATOLOGICALS
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as diarylthioethers. These are organosulfur compounds containing a thioether group that is substituted by two aryl groups.
- Kingdom
- Organic compounds
- Super Class
- Organosulfur compounds
- Class
- Thioethers
- Sub Class
- Aryl thioethers
- Direct Parent
- Diarylthioethers
- Alternative Parents
- Benzylethers / Thiophenol ethers / Dichlorobenzenes / N-substituted imidazoles / Aryl chlorides / Heteroaromatic compounds / Sulfenyl compounds / Dialkyl ethers / Azacyclic compounds / Organopnictogen compounds show 3 more
- Substituents
- 1,3-dichlorobenzene / Aromatic heteromonocyclic compound / Aryl chloride / Aryl halide / Azacycle / Azole / Benzenoid / Benzylether / Chlorobenzene / Dialkyl ether show 18 more
- Molecular Framework
- Aromatic heteromonocyclic compounds
- External Descriptors
- aryl sulfide, imidazoles, ether, dichlorobenzene (CHEBI:83602)
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- QG05NRB077
- CAS number
- 72479-26-6
- InChI Key
- ZCJYUTQZBAIHBS-UHFFFAOYSA-N
- InChI
- InChI=1S/C24H20Cl2N2OS/c25-19-8-11-22(23(26)14-19)24(15-28-13-12-27-17-28)29-16-18-6-9-21(10-7-18)30-20-4-2-1-3-5-20/h1-14,17,24H,15-16H2
- IUPAC Name
- 1-[2-(2,4-dichlorophenyl)-2-{[4-(phenylsulfanyl)phenyl]methoxy}ethyl]-1H-imidazole
- SMILES
- ClC1=CC(Cl)=C(C=C1)C(CN1C=CN=C1)OCC1=CC=C(SC2=CC=CC=C2)C=C1
References
- General References
- External Links
- ChemSpider
- 46840
- 24876
- ChEBI
- 83602
- ChEMBL
- CHEMBL1651990
- Wikipedia
- Fenticonazole
Clinical Trials
- Clinical Trials
Clinical Trial & Rare Diseases Add-on Data Package
Explore 4,000+ rare diseases, orphan drugs & condition pairs, clinical trial why stopped data, & more. Preview package Phase Status Purpose Conditions Count Start Date Why Stopped 100+ additional columns Unlock 175K+ rows when you subscribe.View sample data3 Completed Treatment Bacterial Vaginosis (BV) / Mixed Vaginal Infections / Vaginal Candidiasis / Vaginitis Trichomonal 1 somestatus stop reason just information to hide
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Cream Vaginal 2 % Capsule Vaginal Cream Vaginal Solution Vaginal Spray Cutaneous Suppository Vaginal 600 mg Suppository Vaginal Aerosol, foam Topical Gel Topical Powder Topical Shampoo Topical Solution Topical Cream Topical 2 % Insert Vaginal 600 mg Insert Vaginal 60000000 mg Capsule Vaginal 600 mg Cream Vaginal 2 g Lotion Topical - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.000304 mg/mL ALOGPS logP 6.31 ALOGPS logP 6.94 Chemaxon logS -6.2 ALOGPS pKa (Strongest Basic) 6.77 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 27.05 Å2 Chemaxon Rotatable Bond Count 8 Chemaxon Refractivity 126.14 m3·mol-1 Chemaxon Polarizability 47.63 Å3 Chemaxon Number of Rings 4 Chemaxon Bioavailability 1 Chemaxon Rule of Five No Chemaxon Ghose Filter No Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule Yes Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted MS/MS Spectrum - 10V, Positive (Annotated) Predicted LC-MS/MS splash10-0a4i-0211900000-ca546860e2dcd830129e Predicted MS/MS Spectrum - 10V, Negative (Annotated) Predicted LC-MS/MS splash10-0uei-4050900000-bb5f0cb281224a564134 Predicted MS/MS Spectrum - 20V, Negative (Annotated) Predicted LC-MS/MS splash10-001i-9400000000-51da7e8084136ec31e75 Predicted MS/MS Spectrum - 20V, Positive (Annotated) Predicted LC-MS/MS splash10-056r-9024700000-92c795a64ab2edfcdd31 Predicted MS/MS Spectrum - 40V, Negative (Annotated) Predicted LC-MS/MS splash10-001i-9200000000-393ea65bc7b1a477055d Predicted MS/MS Spectrum - 40V, Positive (Annotated) Predicted LC-MS/MS splash10-00r5-7920100000-81f5d70e89368dc489d7 Predicted 1H NMR Spectrum 1D NMR Not Applicable Predicted 13C NMR Spectrum 1D NMR Not Applicable - Chromatographic Properties
Collision Cross Sections (CCS)
Adduct CCS Value (Å2) Source type Source [M-H]- 194.83487 predictedDeepCCS 1.0 (2019) [M+H]+ 197.19289 predictedDeepCCS 1.0 (2019) [M+Na]+ 203.57552 predictedDeepCCS 1.0 (2019)
Drug created at June 23, 2017 20:42 / Updated at May 05, 2021 20:31