This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Oxiracetam
DrugBank Accession Number
DB13601
Background

Not Available

Type
Small Molecule
Groups
Experimental
Structure
Weight
Average: 158.157
Monoisotopic: 158.06914219
Chemical Formula
C6H10N2O3
Synonyms
  • Oxiracetam
  • Oxiracetamum
External IDs
  • CGP 21690E
  • CT-848
  • ISF 2522

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
1,2-BenzodiazepineThe risk or severity of adverse effects can be increased when 1,2-Benzodiazepine is combined with Oxiracetam.
AcetazolamideThe risk or severity of adverse effects can be increased when Acetazolamide is combined with Oxiracetam.
AcetophenazineThe risk or severity of adverse effects can be increased when Acetophenazine is combined with Oxiracetam.
AclidiniumOxiracetam may increase the central nervous system depressant (CNS depressant) activities of Aclidinium.
AgomelatineThe risk or severity of adverse effects can be increased when Agomelatine is combined with Oxiracetam.
AlfentanilThe risk or severity of adverse effects can be increased when Alfentanil is combined with Oxiracetam.
AlimemazineThe risk or severity of adverse effects can be increased when Alimemazine is combined with Oxiracetam.
AlmotriptanThe risk or severity of adverse effects can be increased when Almotriptan is combined with Oxiracetam.
AlosetronThe risk or severity of adverse effects can be increased when Alosetron is combined with Oxiracetam.
AlprazolamThe risk or severity of adverse effects can be increased when Alprazolam is combined with Oxiracetam.
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Food Interactions
Not Available

Products

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Categories

ATC Codes
N06BX07 — Oxiracetam
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as alpha amino acids and derivatives. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof.
Kingdom
Organic compounds
Super Class
Organic acids and derivatives
Class
Carboxylic acids and derivatives
Sub Class
Amino acids, peptides, and analogues
Direct Parent
Alpha amino acids and derivatives
Alternative Parents
Pyrrolidine-2-ones / N-alkylpyrrolidines / Tertiary carboxylic acid amides / Secondary alcohols / Primary carboxylic acid amides / Lactams / Azacyclic compounds / Organopnictogen compounds / Organonitrogen compounds / Organic oxides
show 2 more
Substituents
2-pyrrolidone / Alcohol / Aliphatic heteromonocyclic compound / Alpha-amino acid or derivatives / Azacycle / Carbonyl group / Carboxamide group / Hydrocarbon derivative / Lactam / N-alkylpyrrolidine
show 12 more
Molecular Framework
Aliphatic heteromonocyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
P7U817352G
CAS number
62613-82-5
InChI Key
IHLAQQPQKRMGSS-UHFFFAOYSA-N
InChI
InChI=1S/C6H10N2O3/c7-5(10)3-8-2-4(9)1-6(8)11/h4,9H,1-3H2,(H2,7,10)
IUPAC Name
2-(4-hydroxy-2-oxopyrrolidin-1-yl)acetamide
SMILES
NC(=O)CN1CC(O)CC1=O

References

General References
Not Available
ChemSpider
4465
RxNav
32645
ChEBI
134788
ChEMBL
CHEMBL36633
Wikipedia
Oxiracetam

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2CompletedTreatmentCraniocerebral Injuries1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Tablet
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility477.0 mg/mLALOGPS
logP-2.2ALOGPS
logP-2.6ChemAxon
logS0.48ALOGPS
pKa (Strongest Acidic)14.61ChemAxon
pKa (Strongest Basic)-2.8ChemAxon
Physiological Charge0ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count2ChemAxon
Polar Surface Area83.63 Å2ChemAxon
Rotatable Bond Count2ChemAxon
Refractivity36.27 m3·mol-1ChemAxon
Polarizability14.76 Å3ChemAxon
Number of Rings1ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSNot Available
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSNot Available

Drug created at June 23, 2017 20:45 / Updated at February 21, 2021 18:54