Carbaspirin calcium

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Carbaspirin calcium
Accession Number
DB13612
Description
Not Available
Type
Small Molecule
Groups
Experimental, Investigational
Structure
Thumb
Weight
Average: 458.436
Monoisotopic: 458.0638211
Chemical Formula
C19H18CaN2O9
Synonyms
  • Carbasalate calcium
  • Carbasalato calcico
  • Carbasalatum calcicum
  • Carbaspirin calcium

Pharmacology

Pharmacology
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Indication
Not Available
Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
Medicalerrors
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AbacavirCarbaspirin calcium may decrease the excretion rate of Abacavir which could result in a higher serum level.
AbciximabThe risk or severity of bleeding and hemorrhage can be increased when Carbaspirin calcium is combined with Abciximab.
AcarboseCarbaspirin calcium may increase the hypoglycemic activities of Acarbose.
AcebutololCarbaspirin calcium may decrease the antihypertensive activities of Acebutolol.
AceclofenacThe therapeutic efficacy of Carbaspirin calcium can be decreased when used in combination with Aceclofenac.
AcemetacinThe risk or severity of adverse effects can be increased when Carbaspirin calcium is combined with Acemetacin.
AcenocoumarolThe risk or severity of bleeding and hemorrhage can be increased when Carbaspirin calcium is combined with Acenocoumarol.
AcetazolamideThe risk or severity of adverse effects can be increased when Carbaspirin calcium is combined with Acetazolamide.
AcetohexamideCarbaspirin calcium may increase the hypoglycemic activities of Acetohexamide.
AcetyldigitoxinThe serum concentration of Acetyldigitoxin can be decreased when it is combined with Carbaspirin calcium.
Interactions
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Food Interactions
Not Available

Products

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Categories

ATC Codes
N02BA15 — Carbasalate calciumB01AC08 — Carbasalate calcium
Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as acylsalicylic acids. These are o-acylated derivatives of salicylic acid.
Kingdom
Organic compounds
Super Class
Benzenoids
Class
Benzene and substituted derivatives
Sub Class
Benzoic acids and derivatives
Direct Parent
Acylsalicylic acids
Alternative Parents
Phenol esters / Benzoic acids / Phenoxy compounds / Benzoyl derivatives / Dicarboxylic acids and derivatives / Ureas / Carboxylic acid salts / Carboxylic acid esters / Organic calcium salts / Carboxylic acids
show 5 more
Substituents
Acylsalicylic acid / Aromatic homomonocyclic compound / Benzoic acid / Benzoyl / Carbonic acid derivative / Carbonyl group / Carboxylic acid / Carboxylic acid derivative / Carboxylic acid ester / Carboxylic acid salt
show 13 more
Molecular Framework
Not Available
External Descriptors
Not Available

Chemical Identifiers

UNII
N667F17JP1
CAS number
5749-67-7
InChI Key
VYMUGTALCSPLDM-UHFFFAOYSA-L
InChI
InChI=1S/2C9H8O4.CH4N2O.Ca/c2*1-6(10)13-8-5-3-2-4-7(8)9(11)12;2-1(3)4;/h2*2-5H,1H3,(H,11,12);(H4,2,3,4);/q;;;+2/p-2
IUPAC Name
calcium urea bis(2-(acetyloxy)benzoate)
SMILES
[Ca++].NC(N)=O.CC(=O)OC1=CC=CC=C1C([O-])=O.CC(=O)OC1=CC=CC=C1C([O-])=O

References

General References
Not Available
ChemSpider
20651
ChEMBL
CHEMBL3833325
Wikipedia
Carbasalate_calcium

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedTreatmentCardiovascular Disease (CVD) / High Blood Pressure (Hypertension)1
2RecruitingTreatmentAtrial Fibrillation / Cerebral Hemorrhage1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Powder
TabletOral
TabletOral
CapsuleOral
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility0.00848 mg/mLALOGPS
logP3.17ALOGPS
logP1.24ChemAxon
logS-4.7ALOGPS
pKa (Strongest Acidic)3.41ChemAxon
pKa (Strongest Basic)-7.1ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area66.43 Å2ChemAxon
Rotatable Bond Count6ChemAxon
Refractivity55.28 m3·mol-1ChemAxon
Polarizability16.51 Å3ChemAxon
Number of Rings2ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterYesChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on June 23, 2017 20:45 / Updated on February 21, 2021 18:54