Sodium bisulfite

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Sodium bisulfite
Accession Number
DB14015
Description

Sodium bisulfite has been used externally for parasitic skin diseases and as gastrointestinal antiseptic.

Type
Small Molecule
Groups
Approved
Structure
Thumb
Weight
Average: 104.061
Monoisotopic: 103.954409263
Chemical Formula
HNaO3S
Synonyms
  • Bisulfite de sodium
  • Natriumbisulfit
  • Natriumhydrogensulfit
  • primäres Natriumsulfit
  • saures Natriumsulfit
  • sodium bisulphite
  • sodium hydrogen sulfite
  • sodium hydrogensulfite
External IDs
  • E222

Pharmacology

Indication
Not Available
Associated Therapies
Contraindications & Blackbox Warnings
Learn about our commercial Contraindications & Blackbox Warnings data.
Learn More
Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
Learn about our commercial Adverse Effects data.
Learn More
Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
CisplatinThe therapeutic efficacy of Cisplatin can be decreased when used in combination with Sodium bisulfite.
Additional Data Available
  • Extended Description
    Extended Description

    Extended description of the mechanism of action and particular properties of each drug interaction.

    Learn more
  • Severity
    Severity

    A severity rating for each drug interaction, from minor to major.

    Learn more
  • Evidence Level
    Evidence Level

    A rating for the strength of the evidence supporting each drug interaction.

    Learn more
  • Action
    Action

    An effect category for each drug interaction. Know how this interaction affects the subject drug.

    Learn more
Food Interactions
No interactions found.

Products

Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
Nephramine Liq IVSodium bisulfite (40 mg) + Cysteine (13 mg) + Histidine (250 mg) + Isoleucine (560 mg) + L-Lysine (640 mg) + Leucine (880 mg) + Phenylalanine (880 mg) + Racemethionine (880 mg) + Threonine (400 mg) + Tryptophan (200 mg) + Valine (640 mg)SolutionIntravenousB. Braun Medical Inc.1993-12-31Not applicableCanada flag

Categories

Drug Categories
Classification
Not classified

Chemical Identifiers

UNII
TZX5469Z6I
CAS number
7631-90-5
InChI Key
DWAQJAXMDSEUJJ-UHFFFAOYSA-M
InChI
InChI=1S/Na.H2O3S/c;1-4(2)3/h;(H2,1,2,3)/q+1;/p-1
IUPAC Name
sodium hydrogen sulfite
SMILES
[Na+].OS([O-])=O

References

General References
Not Available
ChemSpider
571016
RxNav
1366858
ChEBI
26709
ChEMBL
CHEMBL1689285
Wikipedia
Sodium_bisulfite

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
Injection, solution20 mg/2ml
SolutionIntravenous5.5 g/100ml
SolutionIntravenous
Injection, solutionIntraperitoneal32 mg/100mL
Prices
Not Available
Patents
Not Available

Properties

State
Solid
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP-1.2ChemAxon
pKa (Strongest Acidic)1.7ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count3ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area60.36 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity11.21 m3·mol-1ChemAxon
Polarizability5.43 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleNoChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created on April 25, 2018 16:30 / Updated on June 12, 2020 10:53

Logo pink
Are you a
new drug developer?
Contact us to learn more about our customized products and solutions.
Logo pink
Stay in the know!
As part of our commitment to providing the most up-to-date drug information, we will be releasing #DrugBankUpdates with our newly added curated drug pages.
#DrugBankUpdates