Deoxyribonuclease-1

BE0012829ProteinHumansDNASE1

Serum endocuclease secreted into body fluids by a wide variety of exocrine and endocrine organs (PubMed:11241278, PubMed:2251263, PubMed:2277032). It is acted on by 3 drugs in DrugBank.

Gene name
DNASE1
UniProtKB entry
P24855Swiss-Prot
Cellular location
Secreted
Residues / weight
282 residues · 31,433 Da
Also known as
3.1.21.1 · Deoxyribonuclease I · DNase I · DNL1 · DRNI

Resolves to

Protein
UniProtP24855UniProt nameDNAS1_HUMAN
Gene
HGNCHGNC:2956NCBI Gene1773GeneCardsDNASE1
Pharmacology
KEGGhsa:1773
Structure
PDB4AWN
Drugs

What you can answer from here — as of September 03, 2024

3DrugsApproved to experimental, with action, bond type and pharmacological action
Sign in
11GO termsFunction, process and component, as structured annotations
Sign in
1Pfam domainDomain architecture mapped to Pfam families and clans
Sign in
4+ReferencesStructured and connected to the statements they support
Sign in

Which approved drugs act on Deoxyribonuclease-1, how selective are they, and which programs against it are still in active trials?

Answer this in Biopharma OSSign in to your account

Create a free account or log in to explore the full data card.

Create Account
Log InPaid Account Log In