NS-398

DB14060ExperimentalSmall molecule

NS-398 is a COX-2 inhibitor. It was developed as part of the mechanistic study of the cyclooxygenases.

Mechanism: Pharmacologically active on Prostaglandin G/H synthase 2
Curator reviewed
Formula / weight: C₁₃H₁₈N₂O₅S · 314.357 g/mol (avg)
Code names: NS-398

Resolves to

Compound

Clinical / RWD

Structure

InChIKeyKTDZCOWXCWUPEO-UHFFFAOYSA-NSMILESCS(=O)(=O)NC1=CC=C(C=C1OC1CCCCC1)[N+]([O-])=O

Targets

What you can answer from here — as of January 29, 2025

2Protein targetsEach mapped to UniProt, with action and pharmacological action

Listed above

1,392Drug interactionsStructured to mechanism, not free text

9+ReferencesStructured and connected to the statements they support

Which drugs share a target with NS-398, and which of those have an active Phase 3 trial?

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