Monomethyl fumarate

DB14219ApprovedInvestigationalSmall molecule

Monomethyl fumarate: Overview.

Mechanism: Pharmacologically active on Kelch-like ECH-associated protein 1
Curator reviewed
Formula / weight: C₅H₆O₄ · 130.099 g/mol (avg)
First approval: United States, 2020
Also known as: Fumaric acid monomethyl ester · Methyl hydrogen fumarate
Brand names: Bafiertam

Resolves to

Compound

UNII45IUB1PX8RCAS2756-87-8ChEMBLCHEMBL589586

Clinical / RWD

RxNorm1546433

Structure

InChIKeyNKHAVTQWNUWKEO-NSCUHMNNSA-NSMILESCOC(=O)\C=C\C(O)=O

Targets

Q14145KEAP1

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

365Drug interactionsStructured to mechanism, not free text

5Clinical trialsPhase, status and sponsor resolved per trial

1Marketed productAcross 1 country and 1 labeller

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Monomethyl fumarate, and which of those have an active Phase 3 trial?

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