Chloride ion

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Name
Chloride ion
Accession Number
DB14547
Description
Not Available
Type
Small Molecule
Groups
Experimental
Structure
Thumb
Weight
Average: 35.453
Monoisotopic: 34.968852707
Chemical Formula
Cl
Synonyms
  • Chloride
  • Chloride (ion)
  • Chloride ions
  • Chloride(1-)
  • Chlorine anion

Pharmacology

Indication
Not Available
Contraindications & Blackbox Warnings
Learn about our commercial Contraindications & Blackbox Warnings data.
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Pharmacodynamics
Not Available
Mechanism of action
Not Available
Absorption
Not Available
Volume of distribution
Not Available
Protein binding
Not Available
Metabolism
Not Available
Route of elimination
Not Available
Half-life
Not Available
Clearance
Not Available
Adverse Effects
Learn about our commercial Adverse Effects data.
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Toxicity
Not Available
Affected organisms
Not Available
Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AcebutololThe therapeutic efficacy of Chloride ion can be decreased when used in combination with Acebutolol.
AlfuzosinThe therapeutic efficacy of Chloride ion can be decreased when used in combination with Alfuzosin.
AmitriptylineThe therapeutic efficacy of Chloride ion can be decreased when used in combination with Amitriptyline.
AmitriptylinoxideThe risk or severity of hypertension can be increased when Amitriptylinoxide is combined with Chloride ion.
AmoxapineThe therapeutic efficacy of Chloride ion can be decreased when used in combination with Amoxapine.
AripiprazoleThe therapeutic efficacy of Chloride ion can be decreased when used in combination with Aripiprazole.
Aripiprazole lauroxilThe therapeutic efficacy of Chloride ion can be decreased when used in combination with Aripiprazole lauroxil.
AsenapineThe therapeutic efficacy of Chloride ion can be decreased when used in combination with Asenapine.
AtenololThe therapeutic efficacy of Chloride ion can be decreased when used in combination with Atenolol.
Benzylpenicilloyl polylysineChloride ion may decrease effectiveness of Benzylpenicilloyl polylysine as a diagnostic agent.
Additional Data Available
  • Extended Description
    Extended Description

    Extended description of the mechanism of action and particular properties of each drug interaction.

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  • Severity
    Severity

    A severity rating for each drug interaction, from minor to major.

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  • Evidence Level
    Evidence Level

    A rating for the strength of the evidence supporting each drug interaction.

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  • Action
    Action

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Food Interactions
Not Available

Products

Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
RurinaChloride ion (0.11 g/1L) + Potassium cation (0.25 g/1L) + Sulfate ion (3.6 g/1L)LiquidTopicalNano Bio Tech Co.,Ltd2017-07-01Not applicableUS flag
RurinaChloride ion (0.11 g/1L) + Potassium cation (0.25 g/1L) + Sulfate ion (3.6 g/1L)LiquidTopicalTELOM-X GENE Co., Ltd.2017-07-01Not applicableUS flag
Telom-X-geneChloride ion (0.11 g/1L) + Potassium cation (0.25 g/1L) + Sulfate ion (3.6 g/1L)LiquidTopicalTELOM-X GENE Co., Ltd.2017-07-01Not applicableUS flag
Unapproved/Other Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
RurinaChloride ion (0.11 g/1L) + Potassium cation (0.25 g/1L) + Sulfate ion (3.6 g/1L)LiquidTopicalNano Bio Tech Co.,Ltd2017-07-01Not applicableUS flag
RurinaChloride ion (0.11 g/1L) + Potassium cation (0.25 g/1L) + Sulfate ion (3.6 g/1L)LiquidTopicalTELOM-X GENE Co., Ltd.2017-07-01Not applicableUS flag
Telom-X-geneChloride ion (0.11 g/1L) + Potassium cation (0.25 g/1L) + Sulfate ion (3.6 g/1L)LiquidTopicalTELOM-X GENE Co., Ltd.2017-07-01Not applicableUS flag

Categories

Drug Categories
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of inorganic compounds known as homogeneous halogens. These are inorganic non-metallic compounds in which the largest atom is a nobel gas.
Kingdom
Inorganic compounds
Super Class
Homogeneous non-metal compounds
Class
Homogeneous halogens
Sub Class
Not Available
Direct Parent
Homogeneous halogens
Alternative Parents
Not Available
Substituents
Homogeneous halogen
Molecular Framework
Not Available
External Descriptors
halide anion, monoatomic chlorine (CHEBI:17996) / an anion (CL-)

Chemical Identifiers

UNII
Q32ZN48698
CAS number
16887-00-6
InChI Key
VEXZGXHMUGYJMC-UHFFFAOYSA-M
InChI
InChI=1S/ClH/h1H/p-1
IUPAC Name
chloride
SMILES
[Cl-]

References

General References
Not Available
Human Metabolome Database
HMDB0000492
KEGG Compound
C00698
ChemSpider
306
BindingDB
26979
RxNav
153974
ChEBI
17996
ChEMBL
CHEMBL19429
PDBe Ligand
CL
Wikipedia
Chloride
PDB Entries
102l / 103l / 107l / 108l / 109l / 110l / 111l / 112l / 113l / 114l
show 14085 more

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
4CompletedPreventionGingivitis / Periodontal Diseases / Plaque, Dental1
4CompletedTreatmentPain1
4CompletedTreatmentSurgical Remove of Hemorrhoids1
4TerminatedNot AvailableHip Fracture1
4Unknown StatusPreventionBacteriuria / Hospital Acquired Infections / Urinary Tract Infection1
4Unknown StatusTreatmentIllness, Critical / Shock1
3Active Not RecruitingTreatmentAdvanced Urothelial Carcinoma / Metastatic Bladder Urothelial Carcinoma / Metastatic Hormone Refractory Prostate Cancer / Metastatic Renal Pelvis Urothelial Carcinoma / Metastatic Ureter Urothelial Carcinoma / Metastatic Urethral Urothelial Carcinoma / Stage IV Bladder Urothelial Carcinoma AJCC v7 / Stage IV Prostate Cancer AJCC v7 / Stage IV Renal Pelvis Cancer AJCC v7 / Stage IV Ureter Cancer AJCC v7 / Stage IV Urethral Cancer AJCC v7 / Unresectable Urothelial Carcinoma / Urothelial carcinoma ureter metastatic1
3Active Not RecruitingTreatmentAnaplastic Ependymoma / Brain Ependymoma / Cellular Ependymoma / Clear Cell Ependymoma / Ependymomas / Papillary Ependymoma1
3Active Not RecruitingTreatmentAnaplastic Medulloblastoma / Medulloblastomas1
3Active Not RecruitingTreatmentChildhood Atypical Teratoid/Rhabdoid Tumor1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SolutionIntravenous129.3 mEq/L
LiquidTopical
SolutionIntravenous12 g/L
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
logP0.61ChemAxon
pKa (Strongest Acidic)-7ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count0ChemAxon
Hydrogen Donor Count0ChemAxon
Polar Surface Area0 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity5.62 m3·mol-1ChemAxon
Polarizability2.39 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
SpectrumSpectrum TypeSplash Key
Predicted MS/MS Spectrum - 10V, Positive (Annotated)Predicted LC-MS/MSsplash10-000i-9000000000-c4fb3d037fe2e74c2a5e
Predicted MS/MS Spectrum - 20V, Positive (Annotated)Predicted LC-MS/MSsplash10-000i-9000000000-c4fb3d037fe2e74c2a5e
Predicted MS/MS Spectrum - 40V, Positive (Annotated)Predicted LC-MS/MSsplash10-000i-9000000000-c4fb3d037fe2e74c2a5e
Predicted MS/MS Spectrum - 10V, Negative (Annotated)Predicted LC-MS/MSsplash10-001i-9000000000-d488e6da5c7ecb77869a
Predicted MS/MS Spectrum - 20V, Negative (Annotated)Predicted LC-MS/MSsplash10-001i-9000000000-d488e6da5c7ecb77869a
Predicted MS/MS Spectrum - 40V, Negative (Annotated)Predicted LC-MS/MSsplash10-001i-9000000000-d488e6da5c7ecb77869a

Drug created on July 12, 2018 15:42 / Updated on June 12, 2020 10:53

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