A synthetic cyclic dinucleotide (CDN) and agonist of stimulator of interferon genes protein (STING), with potential immunoactivating and antineoplastic activities. Upon intratumoral (IT) administration, STING agonist MK-1454 binds to STING... Upon intratumoral (IT) administration, STING agonist MK-1454 binds to STING and activates the STING pathway, which promotes IKK-related kinase TANK-binding kinase 1 (TBK1) signaling and activates nuclear factor-kappa B (NF-kB) and interferon regulatory factor 3...
- Mechanism
- Curator reviewed
Pharmacologically active on Stimulator of interferon genes protein
- Code names
- MK-1454
Resolves to
What you can answer from here — as of July 07, 2026
Which drugs share a target with Ulevostinag, and which of those have an active Phase 3 trial?
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