This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.
Identification
- Generic Name
- Racephedrine
- DrugBank Accession Number
- DB14752
- Background
Not Available
- Type
- Small Molecule
- Groups
- Approved, Experimental
- Structure
Structure for Racephedrine (DB14752)
- Weight
- Average: 165.236
Monoisotopic: 165.115364107 - Chemical Formula
- C10H15NO
- Synonyms
- (+-)-Ephedrine
- Ephedrine DL-form
- Racephedrine
Pharmacology
- Indication
Not Available
Reduce drug development failure ratesBuild, train, & validate machine-learning modelswith evidence-based and structured datasets.Build, train, & validate predictive machine-learning models with structured datasets.- Contraindications & Blackbox Warnings
Avoid life-threatening adverse drug eventsImprove clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.Avoid life-threatening adverse drug events & improve clinical decision support.- Pharmacodynamics
Not Available
- Mechanism of action
- Not Available
- Absorption
Not Available
- Volume of distribution
Not Available
- Protein binding
Not Available
- Metabolism
- Not Available
- Route of elimination
Not Available
- Half-life
Not Available
- Clearance
Not Available
- Adverse Effects
Improve decision support & research outcomesWith structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.Improve decision support & research outcomes with our structured adverse effects data.- Toxicity
Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Drug Interaction Integrate drug-drug
interactions in your softwareAcebutolol The therapeutic efficacy of Racephedrine can be decreased when used in combination with Acebutolol. Alfuzosin The therapeutic efficacy of Racephedrine can be decreased when used in combination with Alfuzosin. Amitriptyline The therapeutic efficacy of Racephedrine can be decreased when used in combination with Amitriptyline. Amitriptylinoxide The risk or severity of hypertension can be increased when Amitriptylinoxide is combined with Racephedrine. Amoxapine The therapeutic efficacy of Racephedrine can be decreased when used in combination with Amoxapine. Aripiprazole The therapeutic efficacy of Racephedrine can be decreased when used in combination with Aripiprazole. Aripiprazole lauroxil The therapeutic efficacy of Racephedrine can be decreased when used in combination with Aripiprazole lauroxil. Asenapine The therapeutic efficacy of Racephedrine can be decreased when used in combination with Asenapine. Atenolol The therapeutic efficacy of Racephedrine can be decreased when used in combination with Atenolol. Benzylpenicilloyl polylysine Racephedrine may decrease effectiveness of Benzylpenicilloyl polylysine as a diagnostic agent. 
Identify potential medication risksEasily compare up to 40 drugs with our drug interaction checker.Get severity rating, description, and management advice.Learn more - Food Interactions
- Not Available
Products
Drug product information from 10+ global regionsOur datasets provide approved product information including:dosage, form, labeller, route of administration, and marketing period.Access drug product information from over 10 global regions.- Over the Counter Products
Name Dosage Strength Route Labeller Marketing Start Marketing End Region Image Chi Formula Capsule 4.2 mg Oral Natures Sunshine Products, Inc. 1995-12-31 2006-07-10 Canada 
Ephedra Capsule 8 mg / cap Oral Champion's Choice Advanced Nutrition Inc. 1997-06-11 1999-08-28 Canada Ephedra Capsule 8 mg Oral Natural Balance 2002-01-14 2009-08-17 Canada Fyto-HB Tea - 10mg/pck Kit; Liquid 10 mg / pck Oral Fytoresearch Inc. 1997-09-25 2002-11-14 Canada Pro-enz 99 Tablet 8 mg Oral Abundance Naturally Ltd 1999-02-01 2009-07-23 Canada Pro-enz 99 Tablet 8 mg Oral Country Road Naturals Inc. 2001-05-01 2003-07-08 Canada Slm Form - Tab Tablet 8 mg Oral Natural Balance 1995-12-31 2003-09-22 Canada Zand Decongestant Herbal Cap Capsule 4 mg Oral Zand Herbal Formulas 1995-12-31 2003-06-20 Canada
Categories
- Drug Categories
- Classification
- Not classified
- Affected organisms
- Not Available
Chemical Identifiers
- UNII
- 03VRY66076
- CAS number
- 90-81-3
- InChI Key
- KWGRBVOPPLSCSI-PSASIEDQSA-N
- InChI
- InChI=1S/C10H15NO/c1-8(11-2)10(12)9-6-4-3-5-7-9/h3-8,10-12H,1-2H3/t8-,10-/m1/s1
- IUPAC Name
- (1S,2R)-2-(methylamino)-1-phenylpropan-1-ol
- SMILES
- CN[C@H](C)[C@@H](O)C1=CC=CC=C1
References
- General References
- Not Available
- External Links
- ChemSpider
- 9085
- ChEMBL
- CHEMBL2110656
- ZINC
- ZINC000000074840
- Wikipedia
- Ephedrine
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Capsule Oral 4.2 mg Capsule Oral 8 mg / cap Capsule Oral 8 mg Kit; liquid Oral 10 mg / pck Tablet Oral 8 mg Capsule Oral 4 mg - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Not Available
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 8.26 mg/mL ALOGPS logP 1 ALOGPS logP 1.32 Chemaxon logS -1.3 ALOGPS pKa (Strongest Acidic) 13.89 Chemaxon pKa (Strongest Basic) 9.52 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 2 Chemaxon Polar Surface Area 32.26 Å2 Chemaxon Rotatable Bond Count 3 Chemaxon Refractivity 49.69 m3·mol-1 Chemaxon Polarizability 18.87 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
- Not Available
Drug created at March 05, 2019 17:14 / Updated at September 30, 2023 15:27