Danvatirsen

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Danvatirsen
DrugBank Accession Number
DB14825
Background

Danvatirsen is under investigation in clinical trial NCT03334617 (Phase II Umbrella Study of Novel Anti-cancer Agents in Patients With NSCLC Who Progressed on an Anti-PD-1/PD-L1 Containing Therapy.).

Type
Biotech
Groups
Investigational
Synonyms
  • Danvatirsen
External IDs
  • AZD9150

Pharmacology

Indication

Not Available

Pharmacology
Reduce drug development failure rates
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Contraindications & Blackbox Warnings
Contraindications
Avoid life-threatening adverse drug events
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Avoid life-threatening adverse drug events & improve clinical decision support.
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Adverseeffects
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With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.
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Improve decision support & research outcomes with our structured adverse effects data.
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
31N550RD05
CAS number
1402357-06-5

References

General References
Not Available
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2Active Not RecruitingTreatmentAdvanced Colorectal Carcinoma / Advanced Non-Small Cell Lung Carcinoma / Mismatch Repair-deficient (dMMR) / Non-Small Cell Lung Carcinoma (NSCLC) / Refractory Colorectal Carcinoma / Refractory Lung Carcinoma / Refractory Pancreatic Carcinoma / Stage II Pancreatic Cancer AJCC v8 / Stage III Colorectal Cancer AJCC v8 / Stage III Lung Cancer AJCC v8 / Stage III Pancreatic Cancer AJCC v8 / Stage IIIA Colorectal Cancer AJCC v8 / Stage IIIA Lung Cancer AJCC v8 / Stage IIIB Colorectal Cancer AJCC v8 / Stage IIIB Lung Cancer AJCC v8 / Stage IIIC Colorectal Cancer AJCC v8 / Stage IIIC Lung Cancer AJCC v8 / Stage IV Colorectal Cancer AJCC v8 / Stage IV Lung Cancer AJCC v8 / Stage IV Pancreatic Cancer AJCC v8 / Stage IVA Colorectal Cancer AJCC v8 / Stage IVA Lung Cancer AJCC v8 / Stage IVB Colorectal Cancer AJCC v8 / Stage IVB Lung Cancer AJCC v8 / Stage IVC Colorectal Cancer AJCC v81
2Active Not RecruitingTreatmentAdvanced Solid Tumors & Metastatic Squamous Cell Carcinoma of the Head and Neck1
2CompletedTreatmentEarly Stage / Non-Small Cell Lung Carcinoma (NSCLC) / Resectable1
2RecruitingTreatmentNon-Small Cell Lung Carcinoma (NSCLC)1
2TerminatedTreatmentAscites / Gastrointestinal Cancers / Neoplasms, Gastrointestinal / Neoplasms, Ovarian / Ovarian Cancer1
1Active Not RecruitingTreatmentAdvanced Solid Tumours1
1Active Not RecruitingTreatmentMetastatic Non-Small Cell Lung Cancer1
1Active Not RecruitingTreatmentMuscle Invasive Bladder Cancer1
1CompletedTreatmentAdvanced Adult Hepatocellular Carcinoma / Metastatic Hepatocellular Carcinoma1
1CompletedTreatmentAdvanced Solid Malignancies1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on May 20, 2019 14:29 / Updated on February 21, 2021 18:54