Nebicapone

DB14849InvestigationalSmall molecule

Nebicapone is under investigation in clinical trial NCT03097211 (Effect of BIA 6-512 at Steady-state on the Levodopa Pharmacokinetics With a Single-dose of Levodopa/Benserazide 200/50 mg or With a Single-dose of...

Mechanism: Pharmacologically active on Catechol O-methyltransferase
Curator reviewed
Formula / weight: C₁₄H₁₁NO₅ · 273.244 g/mol (avg)

Resolves to

Compound

UNIINM2KXJ990TCAS274925-86-9ChEMBLCHEMBL160038

Structure

InChIKeyMRFOLGFFTUGAEB-UHFFFAOYSA-NSMILESOC1=C(O)C(=CC(=C1)C(=O)CC1=CC=CC=C1)[N+]([O-])=O

Targets

P21964COMT

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1Drug interactionStructured to mechanism, not free text

3Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Nebicapone, and which of those have an active Phase 3 trial?

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