Venglustat

DB14966InvestigationalSmall molecule

Venglustat is under investigation in clinical trial NCT01674036 (Safety, Tolerability and Pharmacokinetics of Genz-682452 in Healthy Men).

Mechanism: Pharmacologically active on Ceramide glucosyltransferase
Curator reviewed
Formula / weight: C₂₀H₂₄FN₃O₂S · 389.49 g/mol (avg)
Also known as: Ibiglustat
Code names: GENZ-682452 · GZ-402671 · GZ/SAR-402671 · SAR-402671

Resolves to

Compound

Structure

InChIKeyYFHRCLAKZBDRHN-MRXNPFEDSA-NSMILESCC(C)(NC(=O)O[C@@H]1CN2CCC1CC2)C1=CSC(=N1)C1=CC=C(F)C=C1

Targets

What you can answer from here — as of September 13, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

14Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Venglustat, and which of those have an active Phase 3 trial?

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