GTX-758

DB14969InvestigationalSmall molecule

GTX-758 is under investigation in clinical trial NCT01420861 (GTx-758 on Serum Prostate-specific Antigen (PSA) in Men With Castrate Resistant Prostate Cancer).

Mechanism: Pharmacologically active on Estrogen receptor
Curator reviewed
Formula / weight: C₁₉H₁₃F₂NO₃ · 341.314 g/mol (avg)
Code names: GTX-758

Resolves to

Compound

UNII406GR1485ZCAS938067-78-8ChEMBLCHEMBL3545017

Structure

InChIKeyFBCQEUMZZNVQKD-UHFFFAOYSA-NSMILESOC1=CC=C(C=C1)N(C(=O)C1=CC=C(O)C(F)=C1)C1=CC=C(F)C=C1

Targets

P03372ESR1

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

5+ReferencesStructured and connected to the statements they support

Which drugs share a target with GTX-758, and which of those have an active Phase 3 trial?

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