Estrogen receptor

BE0000123ProteinHumansESR1

Nuclear hormone receptor. It is acted on by 168 drugs in DrugBank.

Gene name
ESR1
UniProtKB entry
P03372Swiss-Prot
Cellular location
Nucleus
Residues / weight
595 residues · 66,215 Da
Also known as
ER · ER-alpha · ESR · Estradiol receptor · NR3A1

Resolves to

Protein
UniProtP03372UniProt nameESR1_HUMAN
Gene
HGNCHGNC:3467NCBI Gene2099GenBank31234GeneCardsESR1
Pharmacology
IUPHAR/GtoPdb620KEGGhsa:2099
Structure
PDB1A52PDB1EREPDB1ERR
Drugs

What you can answer from here — as of September 03, 2024

168DrugsApproved to experimental, with action, bond type and pharmacological action
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74Clinical trialsTrials of drugs acting on it, by phase and status
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36GO termsFunction, process and component, as structured annotations
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4Pfam domainsDomain architecture mapped to Pfam families and clans
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569+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Estrogen receptor, how selective are they, and which programs against it are still in active trials?

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