Enarodustat

DB14985InvestigationalSmall molecule

Enarodustat is under investigation in clinical trial NCT02581124 (Study to Evaluate Effect of Lapatinib on Pharmacokinetics of JTZ-951 in Subjects With End-stage Renal Disease).

Mechanism: Pharmacologically active on Egl nine homolog 1
Curator reviewed
Formula / weight: C₁₇H₁₆N₄O₄ · 340.339 g/mol (avg)
Code names: JTZ-951

Resolves to

Compound

UNIIJSK7TUA223CAS1262132-81-9

Structure

InChIKeyNALAUGMPMIVAOW-UHFFFAOYSA-NSMILESOC(=O)CNC(=O)C1=C(O)C=C(CCC2=CC=CC=C2)N2N=CN=C12

Targets

Q9GZT9EGLN1

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

10Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with Enarodustat, and which of those have an active Phase 3 trial?

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