Fulacimstat

DB15085InvestigationalSmall molecule

Fulacimstat is under investigation in clinical trial NCT02452515 (A Single-blind Pilot Study to Investigate Safety and Tolerability of the Chymase Inhibitor BAY1142524 in Clinically Stable Patients With Left-ventricular Dysfunction).

Mechanism: Pharmacologically active on Chymase
Curator reviewed
Formula / weight: C₂₃H₁₆F₃N₃O₆ · 487.391 g/mol (avg)
Also known as: BAY1142524

Resolves to

Compound

UNIIVIR72PP4ZUCAS1488354-15-9

Structure

InChIKeyJDARDSVOVYVQST-MRXNPFEDSA-NSMILESCN1C(=O)OC2=CC(=CC=C12)N1C=C(C(O)=O)C(=O)N([C@@H]2CCC3=C(C=CC=C23)C(F)(F)F)C1=O

Targets

P23946CMA1

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

4Clinical trialsPhase, status and sponsor resolved per trial

4+ReferencesStructured and connected to the statements they support

Which drugs share a target with Fulacimstat, and which of those have an active Phase 3 trial?

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