Chymase

BE0001038ProteinHumansCMA1

Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. It is acted on by 7 drugs in DrugBank.

Gene name
CMA1
UniProtKB entry
P23946Swiss-Prot
Cellular location
Secreted
Residues / weight
247 residues · 27,325 Da
Also known as
3.4.21.39 · Alpha-chymase · CYH · CYM · Mast cell protease I

Resolves to

What you can answer from here — as of September 07, 2019

7DrugsApproved to experimental, with action, bond type and pharmacological action
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10GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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27+ReferencesStructured and connected to the statements they support
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Which compounds in development act on Chymase, and which indications are they being tested in?

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