PF-06751979

DB15105InvestigationalSmall molecule

PF-06751979 is under investigation in clinical trial NCT03126721 (The Study is to Evaluate the Effect of Multiple Doses PF-06751979 on the Pharmacokinetics of Midazolam in Healthy Adults).

Mechanism: Pharmacologically active on Beta-secretase 1
Curator reviewed
Formula / weight: C₁₈H₁₉F₂N₅O₃S₂ · 455.5 g/mol (avg)
Code names: PF-06751979

Resolves to

Compound

UNII1Y0Y126GUGCAS1818339-66-0ChEMBLCHEMBL3952064

Structure

InChIKeyZLZUHACSRMOLLV-RAALSFIWSA-NSMILESC[C@H]1C[C@H]2CSC(N)=N[C@]2(CO1)C1=NC(NC(=O)C2=NC=C(OC(F)F)C=C2)=CS1

Targets

P56817BACE1

What you can answer from here — as of July 08, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with PF-06751979, and which of those have an active Phase 3 trial?

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