This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Acetic acid C-11
DrugBank Accession Number
DB15111
Background

Acetic acid C-11 is under investigation in clinical trial NCT01953965 (Look at Way the Heart Functions in People With Pulmonary Hypertension (PH) Who Have Near Normal Right Ventricle (RV) Function and People With Pulmonary Hypertension Who Have Impaired RV Function. Using Imaging Studies PET Scan and Cardiac MRI.).

Type
Small Molecule
Groups
Investigational
Structure
Weight
Average: 59.052
Monoisotopic: 59.032563187
Chemical Formula
C2H4O2
Synonyms
  • 11C-ACETATE

Pharmacology

Indication

Not Available

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Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Chemical TaxonomyProvided by Classyfire
Description
This compound belongs to the class of organic compounds known as carboxylic acids. These are compounds containing a carboxylic acid group with the formula -C(=O)OH.
Kingdom
Organic compounds
Super Class
Organic acids and derivatives
Class
Carboxylic acids and derivatives
Sub Class
Carboxylic acids
Direct Parent
Carboxylic acids
Alternative Parents
Monocarboxylic acids and derivatives / Organic oxides / Hydrocarbon derivatives / Carbonyl compounds
Substituents
Aliphatic acyclic compound / Carbonyl group / Carboxylic acid / Hydrocarbon derivative / Monocarboxylic acid or derivatives / Organic oxide / Organic oxygen compound / Organooxygen compound
Molecular Framework
Aliphatic acyclic compounds
External Descriptors
Not Available
Affected organisms
Not Available

Chemical Identifiers

UNII
2A9OM7IPNW
CAS number
78887-71-5
InChI Key
QTBSBXVTEAMEQO-JVVVGQRLSA-N
InChI
InChI=1S/C2H4O2/c1-2(3)4/h1H3,(H,3,4)/i2-1
IUPAC Name
(1-11C)acetic acid
SMILES
C[11C](O)=O

References

General References
Not Available
ChemSpider
396653
RxNav
2550706

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
2CompletedDiagnosticPulmonary Hypertension (PH)1
2TerminatedBasic ScienceHepatocellular Carcinoma1
2TerminatedDiagnosticChronic Thromboembolic Pulmonary Hypertension (CTEPH) / Pulmonary Arterial Hypertension (PAH)1
2TerminatedDiagnosticMild Cognitive Impairment (MCI)1
1RecruitingDiagnosticBenign hepatic neoplasm / Cholangiocarcinoma / Hepatic Metastases / Hepatocellular Carcinoma, Adult / Resectable Hepatocellular Carcinoma1
1, 2CompletedDiagnosticProstate Cancer1
0CompletedDiagnosticProstate Cancer Patients1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available
Predicted Properties
PropertyValueSource
Water Solubility323.0 mg/mLALOGPS
logP-0.12ALOGPS
logP-0.22ChemAxon
logS0.73ALOGPS
pKa (Strongest Acidic)4.54ChemAxon
Physiological Charge-1ChemAxon
Hydrogen Acceptor Count2ChemAxon
Hydrogen Donor Count1ChemAxon
Polar Surface Area37.3 Å2ChemAxon
Rotatable Bond Count0ChemAxon
Refractivity12.64 m3·mol-1ChemAxon
Polarizability5.33 Å3ChemAxon
Number of Rings0ChemAxon
Bioavailability1ChemAxon
Rule of FiveYesChemAxon
Ghose FilterNoChemAxon
Veber's RuleYesChemAxon
MDDR-like RuleNoChemAxon
Predicted ADMET Features
Not Available

Spectra

Mass Spec (NIST)
Not Available
Spectra
Not Available

Drug created at May 20, 2019 14:50 / Updated at June 12, 2020 16:53