Bempegaldesleukin

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Bempegaldesleukin
DrugBank Accession Number
DB15140
Background

Bempegaldesleukin is under investigation in clinical trial NCT03729245 (A Study of NKTR-214 in Combination With Nivolumab Compared With the Investigator's Choice of a Tyrosine Kinase Inhibitor (TKI) Therapy (Either Sunitinib or Cabozantinib Monotherapy) for Advanced Metastatic Renal Cell Carcinoma (RCC)).

Type
Biotech
Groups
Investigational
Synonyms
  • Bempegaldesleukin
External IDs
  • NKTR-214

Pharmacology

Indication

Not Available

Pharmacology
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Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Medicalerrors
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
BNO1JG5MZC
CAS number
1939126-74-5

References

General References
Not Available
Wikipedia
Bempegaldesleukin

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3Active Not RecruitingTreatmentMetastatic Renal Cell Carcinoma / Renal Cell Adenocarcinoma1
3RecruitingTreatmentBladder Tumors / Cancer, Bladder / Muscle Invasive Bladder Cancer1
3RecruitingTreatmentMalignant Melanoma of Skin / Melanoma Stage Iii / Melanoma Stage Iv / Melanomas1
3RecruitingTreatmentMelanomas1
2Active Not RecruitingTreatmentNeoplasms, Metastasis / Urinary Bladder Neoplasms1
2Active Not RecruitingTreatmentSarcomas1
2Not Yet RecruitingTreatmentHead and Neck Carcinoma1
2TerminatedTreatmentMetastatic Castration Resistant Prostate Cancer (mCRPC) / Squamous Cell Carcinoma of the Head and Neck (SCCHN)1
2, 3Not Yet RecruitingTreatmentMetastatic Head and Neck Cancer / Recurrent Head and Neck Cancer1
1Active Not RecruitingTreatmentCoronavirus Disease 2019 (COVID‑19)1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on May 20, 2019 14:52 / Updated on February 21, 2021 18:55