Interleukin-2 receptor subunit beta

BE0000651ProteinHumansIL2RB

Receptor for interleukin-2. It is acted on by 11 drugs in DrugBank.

Gene name
IL2RB
UniProtKB entry
P14784Swiss-Prot
Cellular location
Cell membrane
Residues / weight
551 residues · 61,117 Da
Also known as
High affinity IL-2 receptor subunit beta · IL-2 receptor subunit beta · IL-2R subunit beta · IL-2RB · IL15RB

Resolves to

Protein
UniProtP14784UniProt nameIL2RB_HUMAN
Gene
HGNCHGNC:6009NCBI Gene3560GenBank307048GeneCardsIL2RB
Pharmacology
IUPHAR/GtoPdb1696KEGGhsa:3560
Structure
PDB2B5IPDB2ERJPDB3QAZ
Drugs

What you can answer from here — as of September 07, 2019

11DrugsApproved to experimental, with action, bond type and pharmacological action
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4Clinical trialsTrials of drugs acting on it, by phase and status
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9GO termsFunction, process and component, as structured annotations
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1Pfam domainDomain architecture mapped to Pfam families and clans
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50+ReferencesStructured and connected to the statements they support
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Which approved drugs act on Interleukin-2 receptor subunit beta, how selective are they, and which programs against it are still in active trials?

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