MK-0736

DB15209InvestigationalSmall molecule

MK-0736 is under investigation in clinical trial NCT00679055 (A Study of How MK-0736 Affects Arterial Plaque (0736-006)(TERMINATED)).

Mechanism: Pharmacologically active on 11-beta-hydroxysteroid dehydrogenase 1
Curator reviewed
Formula / weight: C₂₃H₃₀F₃N₃O₂S · 469.57 g/mol (avg)
Code names: MK-0736

Resolves to

Compound

Structure

InChIKeyORQZQBUNAMJFCY-UHFFFAOYSA-NSMILESCCS(=O)(=O)CCCC12CCC(CC1)(CC2)C1=NN=C(N1C)C1=CC=CC=C1C(F)(F)F

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with MK-0736, and which of those have an active Phase 3 trial?

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