MK-0533

DB15242InvestigationalSmall molecule

MK-0533 is under investigation in clinical trial NCT00543959 (Efficacy and Tolerability of MK0533 in Patients With Type 2 Diabetes (0533-005)).

Mechanism: Pharmacologically active on Peroxisome proliferator-activated receptor gamma
Curator reviewed
Formula / weight: C₂₈H₂₄F₃NO₆ · 527.496 g/mol (avg)
Code names: MK-0533

Resolves to

Compound

Structure

InChIKeySTWITCBWQHTJFJ-XMMPIXPASA-NSMILESCC[C@@H](OC1=CC(=CC=C1)N1C(C)=C(C(=O)C2=CC=C(OC)C=C2)C2=CC=C(OC(F)(F)F)C=C12)C(O)=O

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1Clinical trialPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with MK-0533, and which of those have an active Phase 3 trial?

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