VS-4718

DB15273InvestigationalSmall molecule

VS-4718 is under investigation in clinical trial NCT02215629 (Dose Escalation Study in Acute Myeloid or B-Cell Acute Lymphoblastic Leukemia).

Mechanism: Pharmacologically active on Focal adhesion kinase 1
Curator reviewed
Formula / weight: C₂₅H₂₆F₃N₅O₃ · 501.51 g/mol (avg)
Code names: VS-4718

Resolves to

Compound

Structure

InChIKeyIGUBBWJDMLCRIK-UHFFFAOYSA-NSMILESCNC(=O)C1=CC=CC=C1NC1=CC(NC2=C(OC)C=C(C=C2)N2CCOCC2)=NC=C1C(F)(F)F

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

3Clinical trialsPhase, status and sponsor resolved per trial

6+ReferencesStructured and connected to the statements they support

Which drugs share a target with VS-4718, and which of those have an active Phase 3 trial?

Create a free account or log in to explore the full data card.