D-fluoromethyltyrosine F-18

DB15296InvestigationalSmall molecule

D-fluoromethyltyrosine F-18 is under investigation in clinical trial NCT01089998 (PET/CT Imaging for Radiation Dosimetry, Plasma Pharmacokinetics, Safety and Tolerability in Healthy Volunteers and Safety, Tolerability and Diagnostic Performance of BAY86-9596...

Mechanism: Pharmacologically active on Large neutral amino acids transporter small subunit 1
Curator reviewed
Formula / weight: C₁₀H₁₂FNO₃ · 212.211 g/mol (avg)
Code names: BAY86-9596

Resolves to

Compound

UNII58HVN5SR99CAS870452-26-9

Structure

InChIKeyGEBHVOHKNWLITQ-DEVVULMSSA-NSMILESN[C@H](CC1=CC=C(OC[18F])C=C1)C(O)=O

Targets

Q01650SLC7A5

Transporters

Q01650SLC7A5

What you can answer from here — as of October 27, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

1TransporterSubstrate / inhibitor direction, not just membership

Listed above

2Clinical trialsPhase, status and sponsor resolved per trial

2+ReferencesStructured and connected to the statements they support

Which drugs share a target with D-fluoromethyltyrosine F-18, and which of those have an active Phase 3 trial?

Answer this in Biopharma OS Sign in to your account

Create a free account or log in to explore the full data card.

Log In Paid Account Log In