Acebilustat

DB15385InvestigationalSmall molecule

Acebilustat is under investigation in clinical trial NCT01748838 (Phase 1 Study Assessing the Safety and Tolerability of CTX-4430).

Mechanism: Pharmacologically active on Leukotriene A-4 hydrolase
Curator reviewed
Formula / weight: C₂₉H₂₇N₃O₄ · 481.552 g/mol (avg)
Code names: CTX-4430

Resolves to

Compound

Structure

InChIKeyGERJIEKMNDGSCS-DQEYMECFSA-NSMILESOC(=O)C1=CC=C(CN2C[C@@H]3C[C@H]2CN3CC2=CC=C(OC3=CC=C(C=C3)C3=NC=CO3)C=C2)C=C1

Targets

What you can answer from here — as of June 15, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action

Listed above

8Clinical trialsPhase, status and sponsor resolved per trial

3+ReferencesStructured and connected to the statements they support

Which drugs share a target with Acebilustat, and which of those have an active Phase 3 trial?

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