Valoctocogene roxaparvovec

This drug entry is a stub and has not been fully annotated. It is scheduled to be annotated soon.

Identification

Generic Name
Valoctocogene roxaparvovec
DrugBank Accession Number
DB15561
Background

Valoctocogene roxaparvovec is under investigation in clinical trial NCT03392974 (Single-arm Study to Evaluate the Efficacy and Safety of Valoctocogene Roxaparvovec in Hemophilia a Patients at a Dose of 4E13 Vg/kg).

Type
Biotech
Groups
Investigational
Biologic Classification
Gene Therapies
Other gene therapies
Synonyms
  • DNA (synthetic adeno-associated virus 5 vector BMN 270 human blood-coagulation factor VIII SQ variant-specifying)
  • Valoctocogene roxaparvovec
External IDs
  • BMN-270
  • BMN270

Pharmacology

Indication

Not Available

Pharmacology
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Contraindications & Blackbox Warnings
Contraindications
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
Medicalerrors
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Not Available
Food Interactions
Not Available

Categories

Drug Categories
Not Available
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
681K1JDI8M
CAS number
1819334-78-5

References

General References
Not Available
Not Available

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3Active Not RecruitingTreatmentHemophilia A2
3RecruitingTreatmentHemophilia A1
1, 2Active Not RecruitingTreatmentSevere Haemophilia A1
1, 2Enrolling by InvitationTreatmentCoagulation Disorder / Haematological disorders / Hemophilia A / Therapy, Gene1
1, 2RecruitingTreatmentHemophilia A With Anti Factor VIII / Hemophilia A With Inhibitors1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
Not Available
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created on October 17, 2019 15:19 / Updated on February 21, 2021 18:55